Motif ID: NFY{A,B,C}.p2

Z-value: 3.777


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYCchr1_+_409300800.943.9e-08Click!
NFYAchr6_+_411486650.852.5e-05Click!
NFYBchr12_-_1030559240.204.5e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_23175383 7.278 NM_005794
NM_182908
DHRS2

dehydrogenase/reductase (SDR family) member 2

chr17_+_78009895 5.489 NARF
nuclear prelamin A recognition factor
chr17_+_78009819 5.187 NM_001083608
NM_012336
NM_031968
NARF


nuclear prelamin A recognition factor


chr1_+_225194560 5.066 NM_020247
ADCK3
aarF domain containing kinase 3
chr1_+_225194582 4.959 ADCK3
aarF domain containing kinase 3
chr1_+_225194616 4.920 ADCK3
aarF domain containing kinase 3
chr17_-_35827568 4.794 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr1_+_225194622 4.624 ADCK3
aarF domain containing kinase 3
chr17_+_23670247 4.515 NM_014573
TMEM97
transmembrane protein 97
chr17_-_53950191 4.499 NM_004687
MTMR4
myotubularin related protein 4
chr4_-_174492029 4.441 NM_001130688
NM_002129
HMGB2

high-mobility group box 2

chr19_-_14108400 4.357 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr14_-_54438913 4.196 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr17_+_54587641 4.052 NM_018304
PRR11
proline rich 11
chr1_+_110683586 3.829 RBM15
RNA binding motif protein 15
chr1_+_70649451 3.813 NM_001190463
NM_001902
NM_153742
CTH


cystathionase (cystathionine gamma-lyase)


chr1_-_147665783 3.806 HIST2H2BF
histone cluster 2, H2bf
chr1_+_110683580 3.806 RBM15
RNA binding motif protein 15
chrX_+_47999740 3.755 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr2_+_74914742 3.669 HK2
hexokinase 2
chr11_-_67645433 3.665 NM_001277
NM_212469
CHKA

choline kinase alpha

chrX_-_132947141 3.515 GPC3
glypican 3
chr7_-_150305933 3.504 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chrX_+_52797004 3.480 NM_003147
NM_175698
NM_001164417
SSX2

SSX2B
synovial sarcoma, X breakpoint 2

synovial sarcoma, X breakpoint 2B
chrX_-_132947290 3.460 NM_001164617
NM_001164618
NM_001164619
NM_004484
GPC3



glypican 3



chr1_-_180627512 3.436 GLUL
glutamate-ammonia ligase
chr1_-_159257486 3.436 F11R
F11 receptor
chr1_-_27689129 3.418 WASF2
WAS protein family, member 2
chr17_+_78009336 3.393 NM_001038618
NARF
nuclear prelamin A recognition factor
chr19_-_14108267 3.380 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chrX_-_52700674 3.354 NM_173358
SSX7
synovial sarcoma, X breakpoint 7
chr2_+_26862416 3.345 CENPA
centromere protein A
chr6_-_26164478 3.326 NM_005319
HIST1H1C
histone cluster 1, H1c
chr11_-_73371945 3.261 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr15_-_39412032 3.259 NM_007280
OIP5
Opa interacting protein 5
chr17_+_70256397 3.239 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr17_-_45196516 3.231 NM_030802
FAM117A
family with sequence similarity 117, member A
chr17_+_16225130 3.227


chr17_-_77573974 3.207 NM_144998
STRA13
stimulated by retinoic acid 13 homolog (mouse)
chr15_-_20929608 3.138 HERC2P2
hect domain and RLD 2 pseudogene 2
chr17_-_45196465 3.062 FAM117A
family with sequence similarity 117, member A
chr12_+_6473552 3.015 NM_014865
NCAPD2
non-SMC condensin I complex, subunit D2
chr6_-_26305456 3.011 HIST1H3D
histone cluster 1, H3d
chr15_+_39412447 2.984 NUSAP1
nucleolar and spindle associated protein 1
chr2_-_96238296 2.959 NM_020151
STARD7
StAR-related lipid transfer (START) domain containing 7
chr9_+_130883199 2.954 NM_001135917
NM_020438
DOLPP1

dolichyl pyrophosphate phosphatase 1

chr6_+_80771108 2.893 TTK
TTK protein kinase
chr1_-_148080888 2.890 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr16_+_162845 2.881 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr12_+_6473519 2.880 NCAPD2
non-SMC condensin I complex, subunit D2
chr16_-_57221235 2.875 CNOT1
CCR4-NOT transcription complex, subunit 1
chr17_+_70256389 2.857 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr16_+_166678 2.834 NM_000558
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr11_-_67645246 2.829 CHKA
choline kinase alpha
chr1_-_159257567 2.813 F11R
F11 receptor
chr14_+_23654161 2.808 DCAF11
DDB1 and CUL4 associated factor 11
chr17_+_70256341 2.804 NM_004252
SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr6_+_26381122 2.802 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr2_+_238540361 2.791 UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr2_-_61618898 2.779 NM_003400
XPO1
exportin 1 (CRM1 homolog, yeast)
chr14_+_23654307 2.777 NM_181357
DCAF11
DDB1 and CUL4 associated factor 11
chr2_-_96238234 2.751 STARD7
StAR-related lipid transfer (START) domain containing 7
chr1_-_223682394 2.750 NM_002296
LBR
lamin B receptor
chr2_-_128501334 2.711 NM_001145928
NM_024545
SAP130

Sin3A-associated protein, 130kDa

chr1_-_223682324 2.668 LBR
lamin B receptor
chr12_-_120715937 2.659 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr11_-_19219000 2.643 NM_024680
E2F8
E2F transcription factor 8
chr20_+_47096189 2.607 NM_001316
CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr3_-_187771025 2.552 NM_001134415
TBCCD1
TBCC domain containing 1
chr1_+_12002098 2.522 NM_021933
MIIP
migration and invasion inhibitory protein
chr13_-_29937966 2.508 HMGB1
HMGB1P6
high-mobility group box 1
high-mobility group box 1 pseudogene 6
chr6_+_80771040 2.504 NM_001166691
NM_003318
TTK

TTK protein kinase

chr3_-_9414122 2.503 LOC440944
hypothetical LOC440944
chr1_+_12002138 2.495 MIIP
migration and invasion inhibitory protein
chr5_-_149772563 2.483 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr1_-_209915443 2.474 NM_002497
NEK2
NIMA (never in mitosis gene a)-related kinase 2
chr19_-_45948211 2.447 C19orf54
chromosome 19 open reading frame 54
chr17_+_70256370 2.430 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr5_-_131160541 2.407 FNIP1
folliculin interacting protein 1
chr5_+_44844724 2.389 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr5_+_70918856 2.389 NM_022132
MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr16_-_57221240 2.380 NM_016284
NM_206999
CNOT1

CCR4-NOT transcription complex, subunit 1

chr1_+_51968046 2.377 NM_148904
NM_148905
NM_148907
OSBPL9


oxysterol binding protein-like 9


chr6_-_166716353 2.374 BRP44L
brain protein 44-like
chr22_-_27467776 2.351 NM_001005735
NM_007194
NM_145862
CHEK2


CHK2 checkpoint homolog (S. pombe)


chr19_-_1993022 2.346 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr9_+_4782833 2.342 NM_005772
RCL1
RNA terminal phosphate cyclase-like 1
chr2_-_96237665 2.338 STARD7
StAR-related lipid transfer (START) domain containing 7
chr6_+_24883133 2.332 NM_015895
GMNN
geminin, DNA replication inhibitor
chr17_+_54587882 2.330 PRR11
proline rich 11
chr1_+_51968096 2.319 OSBPL9
oxysterol binding protein-like 9
chr14_+_23653848 2.314 DCAF11
DDB1 and CUL4 associated factor 11
chr5_+_70918888 2.312 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr9_+_134895882 2.312 NM_001122823
NM_012087
GTF3C5

general transcription factor IIIC, polypeptide 5, 63kDa

chr15_+_39412183 2.311 NM_001129897
NM_016359
NM_018454
NUSAP1


nucleolar and spindle associated protein 1


chr2_-_234427884 2.303 HJURP
Holliday junction recognition protein
chr14_+_23653745 2.298 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chr1_+_148089251 2.287 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr19_+_50086350 2.283 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr1_-_47552238 2.271 NM_001048166
NM_003035
STIL

SCL/TAL1 interrupting locus

chr2_+_26862368 2.271 NM_001809
NM_001042426
CENPA

centromere protein A

chr13_-_29938029 2.266 NM_002128
HMGB1
high-mobility group box 1
chr2_+_86521999 2.255 NM_001146688
KDM3A
lysine (K)-specific demethylase 3A
chr2_-_234427921 2.254 NM_018410
HJURP
Holliday junction recognition protein
chr9_+_134896194 2.251 GTF3C5
general transcription factor IIIC, polypeptide 5, 63kDa
chr5_+_162820094 2.249 NM_001142556
NM_001142557
NM_012484
NM_012485
HMMR



hyaluronan-mediated motility receptor (RHAMM)



chr1_+_110683467 2.249 NM_022768
RBM15
RNA binding motif protein 15
chr7_-_156495985 2.247 NM_005515
MNX1
motor neuron and pancreas homeobox 1
chr1_-_43945597 2.236 LOC100132774
hypothetical LOC100132774
chr5_+_70918893 2.235 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr5_-_149772469 2.233 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr14_+_23653819 2.231 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr10_-_69267774 2.222 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr11_+_63710206 2.219 STIP1
stress-induced-phosphoprotein 1
chr9_-_6635564 2.184 NM_000170
GLDC
glycine dehydrogenase (decarboxylating)
chr6_+_32515596 2.167 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr19_+_54962075 2.147 AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr6_-_31938530 2.143 NEU1
sialidase 1 (lysosomal sialidase)
chr1_-_195382189 2.135 NM_018136
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr1_+_51968191 2.119 OSBPL9
oxysterol binding protein-like 9
chr5_+_70918935 2.117 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr1_-_28113540 2.116 RPA2
replication protein A2, 32kDa
chr20_-_45418818 2.106 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr6_-_31938572 2.102 NM_000434
NEU1
sialidase 1 (lysosomal sialidase)
chr2_-_111152075 2.102 NM_004336
BUB1
budding uninhibited by benzimidazoles 1 homolog (yeast)
chr1_-_24067347 2.090 NM_000147
FUCA1
fucosidase, alpha-L- 1, tissue
chr2_+_10180304 2.086 NM_001034
RRM2
ribonucleotide reductase M2
chr1_+_210525490 2.066 NM_006243
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr16_+_31792615 2.064 ZNF267
zinc finger protein 267
chr3_+_195336625 2.054 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr19_-_45888259 2.053 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr17_+_43373887 2.050 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr8_+_6553278 2.048 NM_018361
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr14_+_38714111 2.041 NM_002687
PNN
pinin, desmosome associated protein
chr3_-_187770790 2.029 TBCCD1
TBCC domain containing 1
chr2_+_86521939 2.026 KDM3A
lysine (K)-specific demethylase 3A
chr16_+_45281078 1.993 ORC6
PPA2
origin recognition complex, subunit 6
pyrophosphatase (inorganic) 2
chr1_+_148125090 1.992 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chr11_+_63710242 1.989 STIP1
stress-induced-phosphoprotein 1
chr3_+_123036719 1.985 NM_018456
EAF2
ELL associated factor 2
chr7_+_137795387 1.985 NM_003852
NM_015905
TRIM24

tripartite motif containing 24

chr2_+_47483795 1.985 MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr14_-_57834558 1.960 FLJ31306
hypothetical LOC379025
chr10_+_62208256 1.936 CDK1
cyclin-dependent kinase 1
chr16_+_56327168 1.933 KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr3_-_52542748 1.924 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chr20_+_60744231 1.912 NM_016354
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr10_+_62208094 1.904 NM_001170406
NM_001170407
NM_001786
NM_033379
CDK1



cyclin-dependent kinase 1



chr2_+_47483750 1.898 NM_000251
MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr16_-_55042614 1.897 NM_007006
NUDT21
nudix (nucleoside diphosphate linked moiety X)-type motif 21
chr20_+_60744268 1.894 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr1_+_24158887 1.893 NM_017761
PNRC2
proline-rich nuclear receptor coactivator 2
chr17_-_73694669 1.883 NM_003258
TK1
thymidine kinase 1, soluble
chr1_+_24158898 1.881 PNRC2
proline-rich nuclear receptor coactivator 2
chr17_-_77261028 1.871 NM_001040025
ARL16
ADP-ribosylation factor-like 16
chr7_+_98908449 1.869 NM_001013258
NM_213603
ZNF789

zinc finger protein 789

chr19_-_17377383 1.863 NM_004335
BST2
bone marrow stromal cell antigen 2
chr11_+_63710162 1.848 NM_006819
STIP1
stress-induced-phosphoprotein 1
chr6_+_43005214 1.820 CNPY3
canopy 3 homolog (zebrafish)
chr8_-_145612636 1.804 NM_017767
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr15_+_26876480 1.800


chr9_+_4782876 1.798 RCL1
RNA terminal phosphate cyclase-like 1
chr6_+_37245860 1.796 NM_002648
PIM1
pim-1 oncogene
chr10_-_101180191 1.793 NM_002079
GOT1
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chr6_+_26307691 1.792 NM_003522
HIST1H2BF
histone cluster 1, H2bf
chr1_+_51855343 1.786 OSBPL9
oxysterol binding protein-like 9
chr3_+_9414290 1.779 NM_001080517
SETD5
SET domain containing 5
chr11_+_34417109 1.773 CAT
catalase
chr6_-_31890765 1.769 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr7_-_150306169 1.748 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr2_+_10180145 1.747 NM_001165931
RRM2
ribonucleotide reductase M2
chr22_-_40672493 1.735 CENPM
centromere protein M
chr19_+_50086362 1.732 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr1_-_148126089 1.731 NM_175065
HIST2H2AB
HIST2H2BE
histone cluster 2, H2ab
histone cluster 2, H2be
chr2_+_162908869 1.711 GCA
grancalcin, EF-hand calcium binding protein
chr2_+_47483694 1.710 MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr15_+_57184568 1.708 NM_004701
CCNB2
cyclin B2
chr2_-_61618849 1.706 XPO1
exportin 1 (CRM1 homolog, yeast)
chr1_-_148050534 1.706 NM_001024599
NM_001161334
HIST2H2BF

histone cluster 2, H2bf

chr2_-_61618871 1.706 XPO1
exportin 1 (CRM1 homolog, yeast)
chr12_-_26877189 1.705 NM_002223
ITPR2
inositol 1,4,5-triphosphate receptor, type 2
chr1_+_62674913 1.704 NM_003368
USP1
ubiquitin specific peptidase 1
chr1_-_109742020 1.690 NM_002959
SORT1
sortilin 1
chr1_-_19101603 1.687 NM_003748
NM_170726
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr2_+_27128024 1.683 AGBL5
ATP/GTP binding protein-like 5
chr7_+_137795719 1.680 TRIM24
tripartite motif containing 24
chr8_-_145713959 1.676 NM_004260
RECQL4
RecQ protein-like 4
chrX_+_48127911 1.674 NM_001034832
NM_001040612
NM_005636
NM_175729
SSX4B

SSX4

synovial sarcoma, X breakpoint 4B

synovial sarcoma, X breakpoint 4

chr19_+_50086357 1.672 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr16_+_31792578 1.669 NM_003414
ZNF267
zinc finger protein 267
chr3_+_195336631 1.666 HES1
hairy and enhancer of split 1, (Drosophila)
chr4_-_84254873 1.661 PLAC8
placenta-specific 8
chr6_+_43005126 1.651 CNPY3
canopy 3 homolog (zebrafish)
chr1_-_167721723 1.649 NM_006996
SLC19A2
solute carrier family 19 (thiamine transporter), member 2
chr6_-_42821815 1.640 NM_003192
TBCC
tubulin folding cofactor C
chr1_-_35431318 1.638 SFPQ
splicing factor proline/glutamine-rich
chr16_+_2419418 1.636 CCNF
cyclin F
chrX_-_48661226 1.635 NM_006875
PIM2
pim-2 oncogene
chr11_-_46824416 1.626 NM_001008938
NM_014756
CKAP5

cytoskeleton associated protein 5

chr1_+_148726537 1.624 NM_025150
TARS2
threonyl-tRNA synthetase 2, mitochondrial (putative)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.54 3.25e-27 GO:0022403 cell cycle phase
2.98 1.59e-25 GO:0000279 M phase
2.29 4.91e-23 GO:0022402 cell cycle process
2.12 7.46e-23 GO:0007049 cell cycle
2.53 8.40e-23 GO:0000278 mitotic cell cycle
3.17 1.06e-20 GO:0000087 M phase of mitotic cell cycle
2.35 4.96e-19 GO:0051276 chromosome organization
3.09 1.56e-18 GO:0000280 nuclear division
3.09 1.56e-18 GO:0007067 mitosis
2.97 2.55e-17 GO:0048285 organelle fission
4.13 1.22e-14 GO:0065004 protein-DNA complex assembly
3.60 1.94e-14 GO:0071103 DNA conformation change
2.64 2.28e-14 GO:0051301 cell division
3.87 2.36e-14 GO:0006323 DNA packaging
3.97 3.61e-14 GO:0071824 protein-DNA complex subunit organization
1.65 2.17e-13 GO:0006996 organelle organization
2.49 1.18e-12 GO:0010564 regulation of cell cycle process
4.10 1.31e-12 GO:0031497 chromatin assembly
4.10 3.34e-12 GO:0006334 nucleosome assembly
1.51 3.82e-12 GO:0090304 nucleic acid metabolic process
3.84 9.61e-12 GO:0034728 nucleosome organization
2.23 2.01e-11 GO:0006325 chromatin organization
3.35 4.39e-11 GO:0006333 chromatin assembly or disassembly
2.70 3.94e-10 GO:0071156 regulation of cell cycle arrest
2.71 8.81e-10 GO:0000075 cell cycle checkpoint
3.59 1.32e-09 GO:0007059 chromosome segregation
1.29 1.35e-09 GO:0044260 cellular macromolecule metabolic process
2.34 4.52e-09 GO:0051325 interphase
3.83 6.14e-09 GO:0000236 mitotic prometaphase
1.92 6.75e-09 GO:0051726 regulation of cell cycle
2.32 1.50e-08 GO:0051329 interphase of mitotic cell cycle
1.43 1.97e-08 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.45 3.88e-08 GO:0006355 regulation of transcription, DNA-dependent
1.36 6.11e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.90 1.41e-07 GO:0006259 DNA metabolic process
1.32 1.47e-07 GO:0034641 cellular nitrogen compound metabolic process
1.42 1.88e-07 GO:0051252 regulation of RNA metabolic process
1.39 2.50e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.31 6.14e-07 GO:0006807 nitrogen compound metabolic process
1.35 1.12e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.18 1.57e-06 GO:0044237 cellular metabolic process
1.37 1.99e-06 GO:0010468 regulation of gene expression
1.35 2.83e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30 3.59e-06 GO:0060255 regulation of macromolecule metabolic process
1.34 5.64e-06 GO:0071842 cellular component organization at cellular level
1.33 7.27e-06 GO:0071841 cellular component organization or biogenesis at cellular level
1.28 8.47e-06 GO:0031323 regulation of cellular metabolic process
1.33 1.58e-05 GO:0009889 regulation of biosynthetic process
1.33 1.61e-05 GO:0031326 regulation of cellular biosynthetic process
1.27 1.93e-05 GO:0080090 regulation of primary metabolic process
2.65 3.42e-05 GO:0006310 DNA recombination
1.20 7.51e-05 GO:0043170 macromolecule metabolic process
1.16 1.18e-04 GO:0044238 primary metabolic process
2.88 1.70e-04 GO:0007126 meiosis
2.88 1.70e-04 GO:0051327 M phase of meiotic cell cycle
1.30 1.84e-04 GO:0009058 biosynthetic process
2.85 2.26e-04 GO:0051321 meiotic cell cycle
1.23 2.63e-04 GO:0019222 regulation of metabolic process
1.38 2.82e-04 GO:0016070 RNA metabolic process
1.57 3.02e-04 GO:0033554 cellular response to stress
2.43 4.16e-04 GO:0000082 G1/S transition of mitotic cell cycle
1.88 4.20e-04 GO:0034622 cellular macromolecular complex assembly
1.74 4.67e-04 GO:0006974 response to DNA damage stimulus
1.91 6.56e-04 GO:0006281 DNA repair
2.27 7.27e-04 GO:0006260 DNA replication
1.37 9.93e-04 GO:0034645 cellular macromolecule biosynthetic process
1.36 1.10e-03 GO:0009059 macromolecule biosynthetic process
1.86 1.55e-03 GO:0016568 chromatin modification
1.58 1.64e-03 GO:0065003 macromolecular complex assembly
1.23 1.95e-03 GO:0016043 cellular component organization
1.13 1.99e-03 GO:0008152 metabolic process
1.28 2.15e-03 GO:0044249 cellular biosynthetic process
1.22 2.36e-03 GO:0071840 cellular component organization or biogenesis
3.62 2.43e-03 GO:0000819 sister chromatid segregation
1.68 2.99e-03 GO:0034621 cellular macromolecular complex subunit organization
4.37 3.60e-03 GO:0006271 DNA strand elongation involved in DNA replication
6.05 4.14e-03 GO:0051983 regulation of chromosome segregation
5.46 4.21e-03 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
1.61 5.58e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61 5.62e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.99 5.72e-03 GO:0007017 microtubule-based process
1.49 7.55e-03 GO:0043933 macromolecular complex subunit organization
4.05 1.04e-02 GO:0022616 DNA strand elongation
3.82 1.05e-02 GO:0006695 cholesterol biosynthetic process
2.41 1.06e-02 GO:0051320 S phase
1.40 1.41e-02 GO:0044085 cellular component biogenesis
2.68 1.57e-02 GO:0000216 M/G1 transition of mitotic cell cycle
6.79 2.02e-02 GO:0002566 somatic diversification of immune receptors via somatic mutation
6.79 2.02e-02 GO:0016446 somatic hypermutation of immunoglobulin genes
3.45 2.22e-02 GO:0000070 mitotic sister chromatid segregation
1.57 2.38e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
3.09 3.12e-02 GO:0051053 negative regulation of DNA metabolic process
1.43 3.20e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.40 3.83e-02 GO:0022607 cellular component assembly
2.33 4.37e-02 GO:0000086 G2/M transition of mitotic cell cycle
1.29 4.73e-02 GO:0010467 gene expression

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.50 1.78e-42 GO:0005634 nucleus
1.30 1.14e-39 GO:0043227 membrane-bounded organelle
1.30 1.18e-39 GO:0043231 intracellular membrane-bounded organelle
1.26 6.70e-37 GO:0043226 organelle
1.26 8.85e-37 GO:0043229 intracellular organelle
1.19 5.87e-33 GO:0044424 intracellular part
1.17 6.55e-31 GO:0005622 intracellular
2.74 9.39e-30 GO:0005694 chromosome
2.80 7.50e-26 GO:0044427 chromosomal part
1.60 2.69e-19 GO:0070013 intracellular organelle lumen
1.61 9.37e-19 GO:0044428 nuclear part
1.32 1.26e-18 GO:0044446 intracellular organelle part
1.57 1.49e-18 GO:0031974 membrane-enclosed lumen
1.57 6.90e-18 GO:0043233 organelle lumen
1.31 7.16e-18 GO:0044422 organelle part
1.65 9.21e-18 GO:0031981 nuclear lumen
2.90 1.49e-14 GO:0000785 chromatin
1.46 1.49e-13 GO:0043228 non-membrane-bounded organelle
1.46 1.49e-13 GO:0043232 intracellular non-membrane-bounded organelle
1.67 6.69e-13 GO:0005654 nucleoplasm
3.81 9.49e-12 GO:0032993 protein-DNA complex
3.32 9.87e-12 GO:0000793 condensed chromosome
4.69 1.43e-11 GO:0000786 nucleosome
1.33 5.80e-10 GO:0032991 macromolecular complex
2.85 6.70e-10 GO:0044454 nuclear chromosome part
2.62 1.03e-09 GO:0000228 nuclear chromosome
3.06 5.59e-09 GO:0000775 chromosome, centromeric region
4.02 3.75e-07 GO:0000794 condensed nuclear chromosome
2.47 1.67e-06 GO:0005819 spindle
1.74 1.88e-06 GO:0015630 microtubule cytoskeleton
3.22 3.16e-05 GO:0000779 condensed chromosome, centromeric region
2.99 5.46e-05 GO:0000776 kinetochore
6.24 1.02e-04 GO:0042613 MHC class II protein complex
3.15 1.78e-04 GO:0000777 condensed chromosome kinetochore
3.22 2.15e-04 GO:0000922 spindle pole
1.25 3.86e-04 GO:0043234 protein complex
1.10 1.14e-03 GO:0005737 cytoplasm
2.86 3.23e-03 GO:0034399 nuclear periphery
1.88 3.86e-03 GO:0005874 microtubule
1.50 4.51e-03 GO:0044451 nucleoplasm part
1.03 4.81e-03 GO:0044464 cell part
1.03 5.01e-03 GO:0005623 cell
4.60 5.49e-03 GO:0000795 synaptonemal complex
6.11 9.49e-03 GO:0000780 condensed nuclear chromosome, centromeric region
1.49 1.66e-02 GO:0044429 mitochondrial part
2.70 3.60e-02 GO:0016363 nuclear matrix
1.53 4.00e-02 GO:0030529 ribonucleoprotein complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.51 6.70e-20 GO:0003676 nucleic acid binding
1.61 1.24e-17 GO:0003677 DNA binding
1.08 9.92e-07 GO:0005488 binding
1.54 2.84e-05 GO:0030528 transcription regulator activity
2.21 2.56e-04 GO:0043566 structure-specific DNA binding
2.43 2.92e-04 GO:0003690 double-stranded DNA binding
1.47 1.19e-03 GO:0001071 nucleic acid binding transcription factor activity
1.47 1.19e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.11 5.76e-03 GO:0005515 protein binding
7.48 8.94e-03 GO:0016885 ligase activity, forming carbon-carbon bonds
7.48 8.94e-03 GO:0032404 mismatch repair complex binding
1.46 1.37e-02 GO:0019899 enzyme binding
4.99 2.90e-02 GO:0030983 mismatched DNA binding
1.30 3.28e-02 GO:0005524 ATP binding
1.30 3.39e-02 GO:0030554 adenyl nucleotide binding
1.47 4.80e-02 GO:0043565 sequence-specific DNA binding