Motif ID: NFY{A,B,C}.p2

Z-value: 3.777


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYCchr1_+_409300800.943.9e-08Click!
NFYAchr6_+_411486650.852.5e-05Click!
NFYBchr12_-_1030559240.204.5e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_23175383 7.278 NM_005794
NM_182908
 DHRS2

dehydrogenase/reductase (SDR family) member 2

chr17_+_78009895 5.489 NARF
nuclear prelamin A recognition factor
chr17_+_78009819 5.187 NM_001083608
NM_012336
NM_031968
 NARF


nuclear prelamin A recognition factor


chr1_+_225194560 5.066 NM_020247
 ADCK3
aarF domain containing kinase 3
chr1_+_225194582 4.959 ADCK3
aarF domain containing kinase 3
chr1_+_225194616 4.920 ADCK3
aarF domain containing kinase 3
chr17_-_35827568 4.794 NM_001067
 TOP2A
topoisomerase (DNA) II alpha 170kDa
chr1_+_225194622 4.624 ADCK3
aarF domain containing kinase 3
chr17_+_23670247 4.515 NM_014573
 TMEM97
transmembrane protein 97
chr17_-_53950191 4.499 NM_004687
 MTMR4
myotubularin related protein 4
chr4_-_174492029 4.441 NM_001130688
NM_002129
 HMGB2

high-mobility group box 2

chr19_-_14108400 4.357 NM_018154
 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr14_-_54438913 4.196 NM_000161
NM_001024024
NM_001024070
NM_001024071
 GCH1



GTP cyclohydrolase 1



chr17_+_54587641 4.052 NM_018304
 PRR11
proline rich 11
chr1_+_110683586 3.829 RBM15
RNA binding motif protein 15
chr1_+_70649451 3.813 NM_001190463
NM_001902
NM_153742
 CTH


cystathionase (cystathionine gamma-lyase)


chr1_-_147665783 3.806 HIST2H2BF
histone cluster 2, H2bf
chr1_+_110683580 3.806 RBM15
RNA binding motif protein 15
chrX_+_47999740 3.755 NM_005635
 SSX1
synovial sarcoma, X breakpoint 1
chr2_+_74914742 3.669 HK2
hexokinase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 96 entries
enrichment   p-value GO term description
6.79 2.02e-02 GO:0002566 somatic diversification of immune receptors via somatic mutation
6.79 2.02e-02 GO:0016446 somatic hypermutation of immunoglobulin genes
6.05 4.14e-03 GO:0051983 regulation of chromosome segregation
5.46 4.21e-03 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
4.37 3.60e-03 GO:0006271 DNA strand elongation involved in DNA replication
4.13 1.22e-14 GO:0065004 protein-DNA complex assembly
4.10 1.31e-12 GO:0031497 chromatin assembly
4.10 3.34e-12 GO:0006334 nucleosome assembly
4.05 1.04e-02 GO:0022616 DNA strand elongation
3.97 3.61e-14 GO:0071824 protein-DNA complex subunit organization
3.87 2.36e-14 GO:0006323 DNA packaging
3.84 9.61e-12 GO:0034728 nucleosome organization
3.83 6.14e-09 GO:0000236 mitotic prometaphase
3.82 1.05e-02 GO:0006695 cholesterol biosynthetic process
3.62 2.43e-03 GO:0000819 sister chromatid segregation
3.60 1.94e-14 GO:0071103 DNA conformation change
3.59 1.32e-09 GO:0007059 chromosome segregation
3.45 2.22e-02 GO:0000070 mitotic sister chromatid segregation
3.35 4.39e-11 GO:0006333 chromatin assembly or disassembly
3.17 1.06e-20 GO:0000087 M phase of mitotic cell cycle

Gene overrepresentation in compartment category:

Showing 1 to 20 of 47 entries
enrichment   p-value GO term description
6.24 1.02e-04 GO:0042613 MHC class II protein complex
6.11 9.49e-03 GO:0000780 condensed nuclear chromosome, centromeric region
4.69 1.43e-11 GO:0000786 nucleosome
4.60 5.49e-03 GO:0000795 synaptonemal complex
4.02 3.75e-07 GO:0000794 condensed nuclear chromosome
3.81 9.49e-12 GO:0032993 protein-DNA complex
3.32 9.87e-12 GO:0000793 condensed chromosome
3.22 3.16e-05 GO:0000779 condensed chromosome, centromeric region
3.22 2.15e-04 GO:0000922 spindle pole
3.15 1.78e-04 GO:0000777 condensed chromosome kinetochore
3.06 5.59e-09 GO:0000775 chromosome, centromeric region
2.99 5.46e-05 GO:0000776 kinetochore
2.90 1.49e-14 GO:0000785 chromatin
2.86 3.23e-03 GO:0034399 nuclear periphery
2.85 6.70e-10 GO:0044454 nuclear chromosome part
2.80 7.50e-26 GO:0044427 chromosomal part
2.74 9.39e-30 GO:0005694 chromosome
2.70 3.60e-02 GO:0016363 nuclear matrix
2.62 1.03e-09 GO:0000228 nuclear chromosome
2.47 1.67e-06 GO:0005819 spindle

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
7.48 8.94e-03 GO:0016885 ligase activity, forming carbon-carbon bonds
7.48 8.94e-03 GO:0032404 mismatch repair complex binding
4.99 2.90e-02 GO:0030983 mismatched DNA binding
2.43 2.92e-04 GO:0003690 double-stranded DNA binding
2.21 2.56e-04 GO:0043566 structure-specific DNA binding
1.61 1.24e-17 GO:0003677 DNA binding
1.54 2.84e-05 GO:0030528 transcription regulator activity
1.51 6.70e-20 GO:0003676 nucleic acid binding
1.47 1.19e-03 GO:0001071 nucleic acid binding transcription factor activity
1.47 1.19e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.47 4.80e-02 GO:0043565 sequence-specific DNA binding
1.46 1.37e-02 GO:0019899 enzyme binding
1.30 3.28e-02 GO:0005524 ATP binding
1.30 3.39e-02 GO:0030554 adenyl nucleotide binding
1.11 5.76e-03 GO:0005515 protein binding
1.08 9.92e-07 GO:0005488 binding